Intra- Versus Extraarticular Injection of Ropivacaine in Total Knee Arthroplasty

Hvidovre University Hospital

Status and phase: Unknown; Phase 4

Conditions: Pain, Postoperative

Treatments: Drug: intraarticular injection with ropivacaine; Drug: extraarticular injection with ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT00632580

H-D-2007-0079

Details and patient eligibility

About

The purpose of this study is to evaluate the optimal site for application of local anesthetics in total knee arthroplasty surgery. The hypothesis is, that improved pain relief is obtained when administering local anesthetics in the tissues sourrounding the knee joint compared to the knee joint itself.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• eligible for elective total knee arthroplasty
• able to speak and understand Danish
• able to give informed consent

Exclusion criteria

• alocohol or medical abuse
• allergies to local anesthetics
• age < 18 yrs.
• intolerance to opioids

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

1

Active Comparator group

Description:

intraarticular injection with local anesthetic

Treatment:

Drug: intraarticular injection with ropivacaine

2

Experimental group

Description:

intracapsular injection with local anesthetic

Treatment:

Drug: extraarticular injection with ropivacaine