Intra Versus Extrahepatic Division of Right Hepatic Vein During Rightsided Hemihepatectomy

Karolinska University Hospital

Status and phase: Unknown; Phase 2

Conditions: Reduction of Peroperative Blood Loss During Liver Resection

Treatments: Procedure: Extrahepatic vein division; Procedure: Intrahepatic division of the right hepatic vein.

Study type: Interventional

Funder types: Other

Identifiers

NCT02041078

2011/563-31/2 (Other Identifier)

Details and patient eligibility

About

Intrahepatic division of the hepatic vein is associated with less blood loss than extrahepatic dissection and division of the right hepatic vein.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hepatic lesion amenable to right sided hemihepatectomy.

Exclusion criteria

• Hepatic lesions not suitable for a anatomical right sided hemihepatectomy.
• Unfit for surgery
• Unwillingness to participate

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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100 participants in 2 patient groups, including a placebo group

Extrahepatic vein division

Placebo Comparator group

Description:

Conventional right sided hemihepatectomy with division of the liver parenchyma with CUSA.

Treatment:

Procedure: Extrahepatic vein division

Intrahepatic vein division

Experimental group

Description:

Conventional right sided hemihepatectomy with division of the liver parenchyma with CUSA and intrahepatic division of the right hepatic vein.

Treatment:

Procedure: Intrahepatic division of the right hepatic vein.