Intraabdominal Pressure Monitoring Urinary Catheter and Kidney Perfusion Pressure

Dang Tan Phat

Status: Begins enrollment this month

Conditions: Acute Kidney Injury

Treatments: Device: Accuryn Foley Catheter; Device: Conventional Foley Catheter(Medline)

Study type: Interventional

Funder types: Other

Identifiers

NCT06989762

2756

Details and patient eligibility

About

The goal of this clinical trial is to determine whether monitoring intra-abdominal pressure (IAP) and adjusting blood pressure accordingly to maintain optimal renal perfusion pressure can reduce the risk of acute kidney injury (AKI) after cardiac surgery.

The main question this study aims to answer is:

• Does IAP-guided blood pressure management improve renal perfusion and lower AKI rates in cardiac surgery patients?

Participants will be randomly assigned to one of two groups:

• Control Group: Standard ICU care with a conventional Foley catheter.
• Intervention Group: Standard ICU care with an IAP-monitoring Foley catheter, where blood pressure is adjusted based on IAP readings to optimize renal perfusion pressure.

All participants will undergo routine blood and urine tests to assess kidney function during their hospital stay.

This study will help determine whether IAP-based hemodynamic management can improve postoperative kidney outcomes and provide a new strategy for AKI prevention in cardiac surgery patients.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults Undergoing cardiac surgery with cardiopulmonary bypass
• Left ventricular ejection fraction (LVEF) < 50%

Exclusion criteria

• Current pregnancy
• ESRD or AKI on dialysis
• Currently on ECMO or Impella
• Emergent surgery

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

100 participants in 2 patient groups

Control Group - Standard ICU Care with Conventional Foley

Active Comparator group

Description:

Participants will receive standard ICU care after cardiac surgery with a conventional Foley catheter. Blood pressure management will follow routine ICU protocols without intra-abdominal pressure (IAP) monitoring.

Treatment:

Device: Conventional Foley Catheter(Medline)

Intervention Group - IAP Monitoring and Renal Perfusion Pressure Optimization

Experimental group

Description:

Participants will receive standard ICU care after cardiac surgery with an IAP-monitoring Foley catheter. Blood pressure will be adjusted based on IAP readings to optimize renal perfusion pressure(41mmHg).

Treatment:

Device: Accuryn Foley Catheter