Intracardiac Echocardiography-Guided Cavotricuspid Isthmus Ablation With a Circular-Shaped Pulsed Field Ablation Catheter

Capital Medical University

Status: Enrolling

Conditions: Atrial Flutter; Atrial Fibrillation (AF)

Treatments: Procedure: ICE-guided CTI ablation with PFA

Study type: Observational

Funder types: Other

Identifiers

NCT07353775

PFA-CTI ablation

Details and patient eligibility

About

This observational study aims to evaluate the effectiveness and safety of a circular-shaped pulsed field ablation (PFA) catheter for CTI ablation under the guidance of intracardiac echocardiography (ICE). The main question it aims to answer is:

Is the circular-shaped PFA catheter an effective and safe tool for achieving acute success for CTI ablation? Patients undergoing CTI ablation with a circular-shaped PFA catheter will be prospectively enrolled.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Paroxysmal or persistent atrial fibrillation
• Aged 18 years or older
• Scheduled for CTI ablation
• Able and willing to provide written informed consent

Exclusion criteria

• Previous CTI ablation
• Significant congenital heart disease or structural anomaly affecting the CTI
• Active intracardiac thrombus
• Pregnancy or lactation
• Severe renal/hepatic insufficiency
• Active systemic infection or sepsis
• Life expectancy of less than 12 months
• Unable to provide written informed consent.