Intracranial Aneurysms and Cognitive Function

University Hospital of North Norway

Status

Terminated

Conditions

Intracranial Aneurysms

Study type

Observational

Funder types

Other

Identifiers

NCT01320306

2010/2292-2

Details and patient eligibility

About

The prevalence rate of intracranial aneurysms in the adult population is close to 5%. Rupture risk of such aneurysms causing subarachnoid hemorrhage (SAH) can be substantial.Most patients suffering from an aneurysmal SAH are in their mid life, i.e., 30 to 60 years old. Aneurysmal SAH may cause disability and mortality. The present study includes a follow-up study and a cross-sectional fMRI study. The purpose of the follow-up study is to monitor patients receiving prophylactic surgical treatment of their un-ruptured aneurysms to examine whether such treatment is associated with cognitive, psychosocial and/or neurologic sequela. The purpose of the cross-sectional fMRI study is to examine the relationship between memory function and brain activity among SAH patients. Memory impairment is often found among aneurysmal SAH patients. Using fMRI can possibly shed some light on whether such memory impairment may be caused by diffuse cerebral damage or a focal damage at the aneurysm site.

Enrollment

100 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients with un-ruptured aneurysms in the anterior communicating artery and the middle cerebral artery.
A subgroup of patients suffering aneurismal subarachnoid hemorrhage.

Exclusion criteria