Intracranial Pressure in Monopolar and Bipolar Hysteroscopy

Kanuni Sultan Suleyman Training and Research Hospital

Status: Completed

Conditions: Intracranial Pressure Increase

Treatments: Procedure: Bipolar hysteroscopy; Procedure: Monopolar hysteroscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT04004923

Huseyin4

Details and patient eligibility

About

Two distinction fluids are used in operative hysteroscopy. One is monopolar and the second is bipolar. The monopolar fluid contains mannitol and the bipolar fluid contains serum physiologic. This study aims to compare intracranial pressure in patients undergoing monopolar and bipolar hysteroscopy.

Full description

Operative hysteroscopy is currently used in the treatment of several diseases including submucosal myomas, polyps, uterine septum, and abnormal intrauterine bleeding. Two different methods for distension of the uterus for hysteroscopy are available currently. One is monopolar and the second is bipolar. The monopolar fluid contains mannitol and the bipolar fluid contains serum physiologic. Passage of the distention fluid into the uterine veins during hysteroscopy might lead to volume overload, water intoxication, hyponatremia, pulmonary edema or brain edema. However, the effect of monopolar hysteroscopy or bipolar hysteroscopy on intracranial pressure in patients undergoing hysteroscopy is unknown. Optic nerve sheath diameter (ONSD) measurement is a surrogate marker of invasive intracranial pressure. This study aims to compare the impact of monopolar and bipolar hysteroscopy on intracranial pressure by using ONSD measurement in patients undergoing hysteroscopy.

Enrollment: 80 patients

Sex: Female

Ages: 18 to 49 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Must be scheduled to hysteroscopy for treatment of uterine myoma, polyp, septum, or for endometrial ablation.

Exclusion criteria

• Postmenopause;
• Kidney disease;
• Cardiovascular disease;
• Glaucoma

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups

Monopolar hysteroscopy

Active Comparator group

Description:

This group of patients will receive Monopolar hysteroscopy for uterine distention.

Treatment:

Procedure: Monopolar hysteroscopy

Bipolar hysteroscopy

Active Comparator group

Description:

This group of patients will receive Monopolar hysteroscopy for uterine distention.

Treatment:

Procedure: Bipolar hysteroscopy