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Intradialytic Aerobic Exercise in CKD Patient

U

Universitas Padjadjaran

Status

Completed

Conditions

Chronic Kidney Diseases

Treatments

Behavioral: Aerobic Exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT06137937
IKFR.10.23

Details and patient eligibility

About

Intradialytic aerobic exercise is not effective in increasing hemodialysis adequacy but is effective in improving physical performance in twice-weekly hemodialysis patients.

Full description

Uremic myopathy occurs in 60-75% of Chronic Kidney Disease (CKD) patients undergoing hemodialysis, which causes a decrease in muscle strength and physical performance. Increasing dialysis adequacy is beneficial in reducing the impact of uremia on muscles. Intradialytic aerobic exercise in thrice-weekly hemodialysis patients has improved dialysis adequacy and physical performance. This study aims to determine the effect of intradialytic aerobic exercise on improving dialysis adequacy and physical performance in twice-weekly hemodialysis patients.

Enrollment

34 patients

Sex

All

Ages

25 to 54 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • End Stage Renal Disease Patient stage 5 with Glomerular Filtration Rate <15mL/minute/1.73m2 aged 25-54 years undergoing hemodialysis two times per week for three months to five years
  • Hemoglobin levels > 8mg/dl
  • Mini-Mental State Examination (MMSE) score of ≥24
  • Hamilton Depression Rating Scale (HDRS) score <25

Exclusion criteria

  • Received aerobic exercise in the last 3 months
  • History of hospitalization in the last 3 months
  • Access for hemodialysis circulation via the femoral vein.
  • IMT <18,5 (underweight) dan ≥35 (obese class II)
  • Non-stable cardiovascular disease, uncontrolled glucose, acute infection disease

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

34 participants in 2 patient groups

Interventional Group
Experimental group
Description:
subjects in the treatment group underwent routine hemodialysis by committing to an intradialysis aerobic exercise program
Treatment:
Behavioral: Aerobic Exercise
Control Group
No Intervention group
Description:
subjects in the control group underwent routine hemodialysis without a physical exercise program

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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