Intramuscular Versus Intravenous Prophylactic Oxytocin for Hemorrhage After Vaginal Delivery (oxytocin)

Hediye Dagdeviren

Status: Unknown

Conditions: Postpartum Hemorrhage

Treatments: Drug: intarvenous and intramusculer 10 IU oxytocin

Study type: Interventional

Funder types: Other

Identifiers

NCT02080104

27-01.14-02-02

Details and patient eligibility

About

Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour following vaginal delivery: A randomised controlled trial

Full description

Prevention of postpartum haemorrhage is essential in the pursuit of improved health care for women. In this study investigators aimed to compare intramuscular oxytocin with intravenous oxytocin for the routine prevention of postpartum haemorrhage in women who deliver vaginally.In some countries, intravenous access can not be provided easily . Intramuscular application is faster , easier and tougher enforcement requires less skill and equipment . For this reason, less educated , which can be applied by those offering health services .

Enrollment: 2 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Research volunteers, the undersigned, pregnant women
2. Only with vaginal delivery (episiotomy and perineal tears can)
3. > 34 weeks or more will be
4. Cephalic presentation will be
5. At low risk of postpartum hemorrhage

Exclusion criteria

1. <18 years
2. Multiple pregnancies
3. The presence of uterine myoma
4. Having postpartum hemorrhage in previous pregnancies
5. Placenta previa, polyhydramnios
6. More than four parity
7. Fetal macrosomia
8. Hb <9mg/dl
9. preeclampsia
10. Uterine anomalies
11. Receiving anticoagulant therapy, suspected coagulopathy
12. > 42 weeks of pregnancy
13. Oxytocin allergy -

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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2 participants in 2 patient groups

intravenous 10 ıu oxytocin

Active Comparator group

Description:

group which 2 ampul prophylactic oxytocin given for third stage of labour intravenously after vaginal delivery

Treatment:

Drug: intarvenous and intramusculer 10 IU oxytocin

intramusculer 10 ıu oxytocin

Experimental group

Description:

group which oxytocin administered intramusculary after vaginal delivery

Treatment:

Drug: intarvenous and intramusculer 10 IU oxytocin