Intranasal Desmopressin vs IV Ketorolac in Renal Colic Pain Control

Shahid Beheshti University of Medical Sciences

Status: Completed

Conditions: Renal Colic

Treatments: Drug: Desmopressin; Drug: Normal Saline; Drug: Ketorolac

Study type: Interventional

Funder types: Other

Identifiers

NCT02937896

688

Details and patient eligibility

About

The aim of this study is the comparison of efficacy of intravenous ketorolac and intranasal desmopressin in renal colic patients pain control.

Full description

40 renal colic patients have been divided into 2 groups randomly, one group has been received 30mg intravenous Ketorolac and 4 puffs nasal Normal Saline while other has been received 40 micrograms nasal Desmopressin and 1cc intravenous Normal Saline. Pain Score before drug administration,also 10, 30 and 60 minutes after drug administration has been measured bye Visual Analogue Scale ( VAS ).

Enrollment: 40 patients

Sex: All

Ages: 16 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• renal colic patients

Exclusion criteria

• history of hypertension and cardiac disease
• pregnant patients
• use of analgesic within 4 hours before intervention

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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40 participants in 2 patient groups

Ketorolac

Experimental group

Description:

30mg ketorolac administrated intravenous and 4 puffs nasal Normal Saline.

Treatment:

Drug: Normal Saline

Drug: Ketorolac

Drug: Normal Saline

Desmopressin

Active Comparator group

Description:

40 microgram nasal desmopressin administrated and 1cc Normal Saline intravenous

Treatment:

Drug: Normal Saline

Drug: Normal Saline

Drug: Desmopressin