Intraocular Pressure, Blood Pressure, Ocular Perfusion and Blood Flow Fluctuations in Glaucoma Patients

Lithuanian University of Health Sciences

Status: Completed

Conditions: Open Angle Glaucoma

Treatments: Device: Color Doppler Imaging

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01304264

37552

Details and patient eligibility

About

To evaluate whether add-on to prostaglandin therapy with twice a day (bid) dorzolamide is statistically superior to twice a day (bid) timolol with regard to increasing ocular blood flow

Full description

Hypotensive treatments for glaucomatous optic neuropathy (GON), depending on their chemical composition can influence the ocular circulation independent of intraocular pressure (IOP) reduction. It is therefore important not only to identify ocular blood flow deficits in GON, but also document the influence of GON treatments on the ocular circulation

Enrollment: 35 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Open angle glaucoma subjects receiving prostaglandin monotherapy in both eyes

Exclusion criteria

• younger than 18 years old
• women of child bearing potential

Trial design

35 participants in 1 patient group

combination topical glaucoma treatment

Description:

timolol or dorzolamide add on latanoprost monotherapy

Treatment:

Device: Color Doppler Imaging