Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination

Larissa University Hospital

Status and phase: Completed; Phase 4

Conditions: Glaucoma; Ocular Hypertension

Treatments: Drug: Bimatoprost and Bimatoprost/Timolol fixed combination.

Study type: Interventional

Funder types: Other

Identifiers

NCT00941096

17062009-136

Details and patient eligibility

About

The purpose of this study is to examine the ocular hypotensive effect of Bimatoprost and the potential additional effect of the Bimatoprost/Timolol fixed combination in eyes with ocular hypertension, primary open angle glaucoma or exfoliation glaucoma.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary open angle glaucoma
• Exfoliation glaucoma
• Ocular hypertension

Exclusion criteria

• Younger than 18 years old
• Inability to understand and/or follow study requirements
• Women of childbearing potential not using reliable birth control, pregnant or lactating women
• History of chronic obstructive pulmonary disease, heart failure, 2nd or 3rd AV block
• Anticipated modification of treatment for systemic hypertension during the study period
• History of ocular herpes, corneal scarring, conventional or laser surgery or macular pathology
• History of allergy, poor tolerability or poor response to study medication
• Best corrected visual acuity less than 0.4
• Significant visual field defect (MD<15.0 dB)

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind