Intraoperative Conversion During Video-assisted Thoracoscopy Resection for Lung Cancer Does Not Alter Survival (ICVATR)

Centre Hospitalier Universitaire, Amiens

Status

Completed

Conditions

Survival

Video-assisted Thoracoscopic Surgery

Surgery

Lung Cancer

Lobectomy

Treatments

Procedure: anatomical resection

Study type

Observational

Funder types

Other

Identifiers

NCT04663191

T38

Details and patient eligibility

About

Anatomical resection with systematic lymph-node dissection is currently the standard of care for the treatment of early stage non-small cell lung cancer. The use of minimally invasive approaches has increased greatly over the last two decades [either video-assisted thoracoscopic surgery (VATS) or robotic-assisted thoracoscopic surgery (RATS)], as they provide the patient with better outcomes than open thoracotomy. Minimally invasive VATS lobectomy for a standard case is generally a straightforward procedure for a well-trained surgical team, although concomitant preoperative pathologies or intraoperative findings/adverse events may result in technical difficulties, leading to intraoperative conversion, commonly by thoracotomy.

The investigators aimed to assess long-term outcomes in a consecutive cohort of patients treated by anatomical pulmonary resection either using VATS, VATS requiring intraoperative conversion to thoracotomy, or upfront open thoracotomy for lung-cancer surgery.

Enrollment

843 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All consecutive patients treated by anatomical lobar pulmonary resection (lobectomy, bilobectomy) or anatomical sublobar pulmonary resection (segmentectomy) for non-small cell lung cancer (NSCLC), either by VATS (eventually with intraoperative conversion) or upfront thoracotomy.

Exclusion criteria

patients with non-anatomical pulmonary resection (wedge resection)
patients with a histology other than NSCLC (benign or metastatic from another primitive cancer), stage IV NSCLC disease,
patients with multiple primary NSCLC (synchronous or metachronous)
patients with incomplete resection (R+)
patient for whom a VATS approach was never considered