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Intraoperative Measurement of Lung Elastance and Transpulmonary Pressure Using Two Different Methods. (Lungbaro)

S

Stefan Lundin

Status

Completed

Conditions

Anesthesia

Treatments

Other: Measurement of lung elastance by two methods

Study type

Observational

Funder types

Other

Identifiers

NCT02830516
LUA-74201

Details and patient eligibility

About

Classically lung elastance and transpulmonary pressure are measured from the difference in tidal variations of airway pressure subtracted by tidal variations i esophagus pressure divided by the tidal volume. This requires the presence of a esophageal balloon catheter which is cumbersome and costly. In this study values obtained as described above are compared to values obtained with a new method in which a stepwise increase in positive endexpiratory pressure (PEEP) is performed with a size which corresponds to the tidal volume which the patient is ventilated with. These measurements are performed in anesthetized patients prior to major surgery.

Full description

Classically lung elastance and transpulmonary pressure are measured from the difference in tidal variations of airway pressure subtracted by tidal variations in esophageal pressure divided by the tidal volume (Method 1). This requires the presence of a esophageal balloon catheter which is cumbersome and costly.

In this study values obtained as described in Method 1 above are compared to values obtained with a new method in which a PEEP-step is performed with a size which corresponds to the tidal volume which the patient is ventilated with. Measurements using Method 1 and 2 are performed in anesthetized patients prior to major surgery.

Enrollment

24 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patient undergoing major surgery during anesthesia and muscle relaxation

Exclusion criteria

  • Patient with chronic obstructive lung disease

Trial design

24 participants in 1 patient group

Lung elastance - transpulmonary pressure
Description:
Lung elastance and transpulmonary pressure measured by tidal esophageal pressure variations and by performing a PEEP step
Treatment:
Other: Measurement of lung elastance by two methods

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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