Intraoperative Pain After Infiltration Technique Using Artpharma Versus Artinibsa in Children

Cairo University (CU) logo

Cairo University (CU)

Status

Unknown

Conditions

Pain, Postoperative

Treatments

Other: Artinibsa
Other: Artpharma

Study type

Interventional

Funder types

Other

Identifiers

NCT04221685
IOP Use Artp Vs Artin inf

Details and patient eligibility

About

The aim of this study is to assess Intraoperative pain for extraction of Maxillary primary molars using Artpharma Versus Artinibsa in children during infiltration technique.

Full description

Articaine is used for pain control Like other local anesthetic drugs, articaine causes a temporary and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.This local anesthesia was first synthesized by Rusching in 1969, and carried to the market in Germany by Hoechst AG, a life-sciences German company, under the brand name Ultracain ,it entered clinical practice in Germany in 1976. The name was changed in 1984, the year it was released in Canada. It then entered the United Kingdom in 1998, the United States in 2000 and Australia in 2005. At this time, articaine is available as a 4% solution containing 1:100, 000 or 1:200, 000 adrenaline. Articaine has been widely used in dental surgery.It started to use carticaine around 1977.In dentistry has been investigated widely. Articaine is a unique amide LA in that it contains a thiophene, instead of a benzene ring.The thiophene ring allows greater lipid solubility and effectiveness as a greater portion of an administered dose can enter neurons

Enrollment

130 estimated patients

Sex

All

Ages

6 to 9 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Children aged 6-9 years.
  • Children with maxillary primary molars indicated for extraction.

Exclusion criteria

  • Children with medical conditions.
  • Uncooperative children.
  • Parents or guardians who refuse participating in the study.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

130 participants in 2 patient groups

Artinibsa
Active Comparator group
Description:
Powerful local anaesthetic with a short latency time. Its high lipid solubility gives it better diffusion through soft tissues and bone and makes it highly effective for infiltrative techniques.4%Articaine 1:100000.
Treatment:
Other: Artinibsa
Artpharma
Experimental group
Description:
ArtPharma is a unique amide local anesthetic that is currently Used in dentistry Amides has taken over their predecessors esters with their enhanced performance.Each ml Articaine (D.C.I) 40.00 mg hydrochloride,Epinephrine (D.C.I) (tartrate) 0.01 mg
Treatment:
Other: Artpharma

Trial contacts and locations

0

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Central trial contact

Hafedha Zain, Master; Fatma Korany Ismail, Phd

Data sourced from clinicaltrials.gov

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