Intraoperative Pectoral Block vs IV Analgesia for Pain After Modified Radical Mastectomy

Islamabad Medical and Dental College

Status and phase: Active, not recruiting; Phase 3

Conditions: Mastectomy, Modified Radical

Treatments: Drug: Ketorolac 30 mg IV; Drug: bupivacaine 0.5% injection

Study type: Interventional

Funder types: Other

Identifiers

NCT07257874

No.179/IMDC/IREB-2025

Details and patient eligibility

About

There is difference in post operative pain between patients receiving inter- pectoral block and those receiving standard Intravenous analgesia(INJ TORADOL) in patients undergoing Modified Radical Mastectomy.

To compare between these two methods , which one is better for post operative pain management.

Enrollment: 60 estimated patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female Patients undergoing Modified Radical Mastectomy for biopsy proven Carcinoma Breast
• Patient with age 18-65 years
• Patients with ASA Grade 2
• BMI less than 40 kg/meter square

Exclusion criteria

• Block site infection
• Coagulopathies (INR > 1.6 and Platelets < 100000)
• Any Organ dysfunction such as severe cardiac, pulmonary, renal or liver dysfunction
• Systemic infection
• Dementia
• Known hypersensitivity to local anesthetic agents

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

PECs Arm

Experimental group

Treatment:

Drug: bupivacaine 0.5% injection

IV Analgesia Arm

Active Comparator group

Treatment:

Drug: Ketorolac 30 mg IV