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Intraoperative Posterior Cruciate Ligament (Transcruciate) Injection After Total Knee Arthroplasty (TKA)

U

University of Saskatchewan

Status and phase

Completed
Phase 4

Conditions

Arthroplasty, Replacement, Knee

Treatments

Procedure: transcruciate injection of 20 cc of 0.5% Ropivacaine
Procedure: transcruciate injection of 20cc of normal saline

Study type

Interventional

Funder types

Other

Identifiers

NCT01345604
PCL block

Details and patient eligibility

About

his study is being done because total knee replacements can leave patients with considerable pain after surgery. Therefore, many studies have been done to find the best ways to control knee pain after the surgery. Currently, a popular approach is to use many different techniques to control the pain. This includes injecting freezing (local anesthetic) into the spinal column (spinal anesthetic), injecting freezing close to the nerves of the knee and using various kinds of medications (e.g. narcotics and anti-inflammatory medications). Studies have shown using this a combination of techniques can reduce pain and allow earlier discharge from the hospital. However, one downside to this approach is it does not usually control the pain in the back of the knee. One new technique has been used to try and overcome this. This technique is called a "posterior cruciate ligament block" or "PCL block". It involves injecting a drug into the back of the knee which will block the nerves in this area. Sometimes the investigators refer to this as "freezing".

The purpose of our study is to determine whether this "PCL Block" will improve pain after the total knee replacement surgery. The investigators will also determine whether this technique will improve movement in the knee and lessen narcotic usage after the surgery.

Enrollment

50 patients

Sex

All

Ages

16 to 100 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • American Society of Anesthesiologists' (ASA) physical status classification (ASA) I and II patients undergoing unilateral total knee arthroplasty at Saskatoon City Hospital
  • Patients recruited from the practice of 4 orthopedic surgeons

Exclusion criteria

  • Inability to obtain informed consent
  • Simultaneous bilateral total knee arthroplasty or revision cases
  • Preexisting neurological deficits in the distribution of the femoral nerve or known diagnosis of peripheral neuropathy
  • Coagulopathies
  • Infection either systemically or at the needle insertion sites
  • Allergies to local anesthetics or opioids
  • Patients with a history of narcotic dependency or chronic pain
  • ASA III and IV
  • Body Mass Index (BMI) > 40

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

50 participants in 2 patient groups, including a placebo group

Saline
Placebo Comparator group
Treatment:
Procedure: transcruciate injection of 20cc of normal saline
Ropivicaine
Active Comparator group
Treatment:
Procedure: transcruciate injection of 20 cc of 0.5% Ropivacaine

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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