Intrapartum Oxytocin Administration Affects Primitive Neonatal Reflexes

Majadahonda Iron Gate University

Status: Completed

Conditions: Bonding; Breastfeeding; Newborn; Perinatal; Oxytocin

Treatments: Drug: Oxytocin

Study type: Observational

Funder types: Other

Identifiers

NCT01891201

PI10/00791

Details and patient eligibility

About

The aim of this study was to assess whether administration of oxytocin intrapartum (Oxt) has any effect on Neonatal Primitive Reflexes (RNP) and if dose dependent. The secondary objective is to assess the effects on exclusive breastfeeding at 3 months

Full description

Patients and Methods Prospective case-control study performed in a tertiary hospital. Cases: mother-child dyads in which Oxt had been administered during the birth process (n = 53). Controls: mother-child dyads without Oxt (n = 45). The RNP were recorded with a camcorder in biological nurturing position. An observer blinded to the group and the dose of Oxt codified the RNP (reach/not reached). To assess the type of breastfeeding telephone call was made at 3 months old RN.

Enrollment: 98 patients

Sex: All

Ages: 1 to 4 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Healthy singleton term infant delivered vaginally with Apgar at 5 min> 7;
• Expressed desire to administer during pregnancy breastfeeding;
• Signed informed consent

Exclusion criteria

• Preterm neonate;
• Fetal chromosomal or other abnormalities diagnosed in utero to modify their adaptation to extrauterine environment;
• Hospitalization of the mother in ICU;
• Hospitalization in the following 48 hours neonate at birth;
• Wish to artificial feeding before parturition;
• Language difficulties;
• Completion of caesarean delivery

Trial design

98 participants in 1 patient group

Not exposed to oxytocin

Description:

Mother-child dyads in which Oxt had not been administered during the birth process

Treatment:

Drug: Oxytocin