Intrathecal Additives for Spinal Anaesthesia in Elective Caesarean Sections

Benha University

Status: Unknown

Conditions: Pain, Postoperative

Treatments: Drug: intrathecal Magnesium; Drug: intrathecal dexamthasone; Drug: intrathecal dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT04747171

spinal additives

Details and patient eligibility

About

we designed this randomized, single -blind, prospective clinical study to test postoperative analgesia of three intrathecal additives in elective caesarean sections which are magnesium, dexamethasone and dexmedetomidine.

Enrollment: 105 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists classII-III adult female patient (age :18 -40 years old )
• Elective cesarean section under spinal anaesthesia
• Gestational age > 37 weeks
• BMI less than 30 kg/m2

Exclusion criteria

• Patient refusal
• unable to give consent
• age < 18 or > 40
• BMI more than 30 kg/m2
• known allergy to the study medication
• coagulopathies or on anticoagulant medications
• diabetic neuropathy
• patients with psychiatric disorders

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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105 participants in 3 patient groups

magnesium intrathecal

Active Comparator group

Treatment:

Drug: intrathecal Magnesium

dexamethasone intrathecal

Active Comparator group

Treatment:

Drug: intrathecal dexamthasone

dexmedetomidine intrathecal

Active Comparator group

Treatment:

Drug: intrathecal dexmedetomidine