Intrathecal Fentanyle Versus Dexamethasone in Gynacological Laparoscopic Surgeries

Assiut University

Status: Completed

Conditions: Intraoperativ Pain

Treatments: Drug: saline; Drug: dexamethasone; Drug: intrathecal fentanyle

Study type: Interventional

Funder types: Other

Identifiers

NCT04779060

13700331

Details and patient eligibility

About

Laparoscopy was first introduced to the medical field of in the middle of the last century. It revolutionized the surgical interventions; it reduced the total medical expenditures and hastened postoperative recovery . General anaesthesia (GA) was considered the only anesthetic technique suitable for laparoscopic interventions, and several myths and facts prevented regional anaesthesia (RA) implementation. Respiratory and Cardiovascular impairment were the main aspects of concern which are thought to be best controlled by GA

Enrollment: 120 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I, II
• elective gynacological laparoscopic surgery

Exclusion criteria

• patient refusal
• chronic kidney and hepatic diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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120 participants in 3 patient groups, including a placebo group

fentanyle group

Active Comparator group

Treatment:

Drug: intrathecal fentanyle

dexamethasone group

Active Comparator group

Treatment:

Drug: dexamethasone

control group

Placebo Comparator group

Treatment:

Drug: saline