Intrathecal Prilocaine and Adductor Canal Block vs Intrathecal Bupivacaine Alone for Ambulatory Knee Arthroscopy

Ain Shams University

Status and phase: Completed; Phase 4

Conditions: Post Operative Pain

Treatments: Drug: spinal anesthesia with bupivacaine; Drug: spinal anesthesia with hyperbaric prilocaine+adductor canal block (ACB) with bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05609565

FMASU MS 706/ 2022

Details and patient eligibility

About

• Although bupivacaine is safe and has a low rate of transient neurologic symptoms, the prolonged sensory and motor block is a drawback for day-case spinal anesthesia.Intrathecal hyperbaric prilocaine causes a much shorter motor block, with a similar onset time and lower inter-individual variability in motor block duration. Furthermore, the peripheral nerve block is used as an adjunct to the spinal anesthesia to prolong the surgical anesthetic conditions.

Enrollment: 80 patients

Sex: All

Ages: 21 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists (ASA) score I-II.
• Body mass index < 35 kg/m2

Exclusion criteria

• Patient's refusal.
• Known coagulopathy.
• Known peripheral neuropathy or neurological deficits.
• Known allergy to study drugs.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups

Group 1

Active Comparator group

Treatment:

Drug: spinal anesthesia with hyperbaric prilocaine+adductor canal block (ACB) with bupivacaine

Group 2

Active Comparator group

Treatment:

Drug: spinal anesthesia with bupivacaine