Intravascular Ultrasound Prediction of Myocardial Size and Coronary Computed Tomography-Derived Ischemic Burden for Coronary Lesion (IVUS-CAMS)

Asan Medical Center

Status: Active, not recruiting

Conditions: Coronary Artery Disease

Treatments: Other: Intravascular Ultrasound, coronary computed tomography angiography

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT02845505

AMCCV 2016-06

Details and patient eligibility

About

The aims of this study are 1) to identify IVUS determinants of the CAMS-derived myocardial territories subtended to the diseased vessels, 2) to find IVUS determinant for the extent of CAMS-derived myocardial size, and 3) to develop the mathematical model that integrates the IVUS information about myocardial territory and stenosis severity and predicts the extent of CAMS-derived myocardial size.

Enrollment: 500 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 20years or older
• Patients who have at least one epicardial coronary artery lesion (including isolated left main disease or side branch) with visually estimated diameter stenosis >50% and take coronary angiography, CT angiography and IVUS
• Willing and able to provide informed written consent

Exclusion criteria

• In-stent restenosis
• Bypass graft
• Suspected coronary spasm even after sufficient nitrate injected
• Cases in which the IVUS imaging catheter failed to cross the lesion
• Poor quality IVUS or CT images
• Visible collateral flow on angiography

Trial design

500 participants in 1 patient group

IVUS-CAMS

Description:

patients who undergo coronary computed tomography angiography, invasive coronary angiography and IVUS

Treatment:

Other: Intravascular Ultrasound, coronary computed tomography angiography