Intravenous Administration of Metoprolol Versus Biatrial Pacing in the Prevention of Atrial Fibrillation After Cardiac Surgery

Kuopio University Hospital

Status and phase: Completed; Phase 4

Conditions: Atrial Fibrillation; Biatrial Pacing; Metoprolol

Treatments: Other: metoprolol, biatrial pacing

Study type: Interventional

Funder types: Other

Identifiers

NCT00783900

KUH5204006

Eudra-CT: 2008-006932-36

Details and patient eligibility

About

The aim of the study is to compare the effectiviness of biatrial pacing versus intravenous administration of metoprolol in the prevention of atrial fibrillation after cardiac surgery

Enrollment: 316 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• elective CABG and aortic valve cardiac patients,
• previous use of beta blocker

Exclusion criteria

• Previous episodes of Atrial fibrillation or flutter,
• II or II degree atrioventricular block, uncontrolled heart failure
• Sick sinus syndrome

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

316 participants in 2 patient groups

metoprolol

Active Comparator group

Treatment:

Other: metoprolol, biatrial pacing

biatrial pacing

Active Comparator group

Treatment:

Other: metoprolol, biatrial pacing