Intravenous Cannulation In Children During Sevoflurane Induction

University Hospital Fattouma Bourguiba

Status: Completed

Conditions: Intravenous Cannulation; Child; Sevoflurane Induction

Treatments: Other: Intravenous Cannulation (iv placement)

Study type: Interventional

Funder types: Other

Identifiers

NCT03851692

0925-0586

Details and patient eligibility

About

The early placement of an intravenous (iv) line in children anesthetized with halothane has been shown safe and acceptable compared with later placement. However, there's not well known with sevoflurane use (2). The aim of the investigator's study is to determine whether one should make iv attempts during the early induction period (at 60seconds) or lately (90 or 120 s) and waiting until the child receives additional sevoflurane inhalation anesthesia

Full description

the investigators conducted a prospective randomized study, after obtaining Institutional review board approval, which didn't require written parental consent. Children age 1-12 years, undergoing elective general anesthesia via an inhalation induction were randomized to one of three groups of 30 patients each one, for iv placement, either 60s (group E), 90 or 120 s (group L) following loss of lid reflex. Movement on iv placement and incidence of laryngospasm were determined. Difficulty with iv placement was also recorded. Statistical analysis included contingency testing, ANOVA, and non parametric testing. A P-value <0.05 was considered significant.

Enrollment: 90 patients

Sex: All

Ages: 1 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I, II
• Age from 1 to 12 years old
• Ambulatory surgery under general anesthesia.

Exclusion criteria

• Age <1 year or> 12 years
• non-ambulatory surgery,
• contraindication for induction with sevoflurane

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 2 patient groups

60s (group E)

Active Comparator group

Description:

Intravenous cannulation was released either 60 s following loss of lid reflex in group E

Treatment:

Other: Intravenous Cannulation (iv placement)

90 or 120 s (groupe L)

Active Comparator group

Description:

Intravenous cannulation was released either 90 or 120 s following loss of lid reflex in group L

Treatment:

Other: Intravenous Cannulation (iv placement)