Intravenous Infusion of Lidocaine in Gastroscopy

Shandong University

Status and phase: Unknown; Phase 4

Conditions: Sedation

Treatments: Drug: placebo; Drug: Lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT04439773

2020SDU-QILU-022

Details and patient eligibility

About

Intravenous infusion of lidocaine significantly reduces incidence of bucking when perfomed gastroscopy.

Full description

This study divide patients into two groups, the patients in lidocaine group will be given lidocaine; the control group will be given placebo .the primary endopiont was to investigate whether intravenous lidocaine can reduce incidence of bucking and movement in sedation of gastroscopy.

Enrollment: 130 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

patients aged >18 years who were scheduled for ERCP at Qilu hospital.

Exclusion criteria

patients with ASA (American Society of Anesthesiologists) Class 4 or 5, pre-existing hypoxemia (SpO2 <90%), hypotension (systolic blood pressure <90 mm Hg), bradycardia (HR<50 beats/min), uncontrolled hypertension (SBP >170 mm Hg, diastolic blood pressure>100 mm Hg), severe renal or liver failure, pregnancy or lactation, allergy to lidocaine, atrioventricular block, epilepsy, and inability to give informed consen

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

130 participants in 2 patient groups, including a placebo group

control group

Placebo Comparator group

Description:

the control group will be given the same volume of saline as the experimental group

Treatment:

Drug: placebo

lidocaine group

Experimental group

Description:

the experimental group will be given l-1.5mg lidocaine and then 2mg/kg/h

Treatment:

Drug: Lidocaine