Intravenous Paracetamol Compared Dexketoprofen for Postoperative Analgesia After Septoplasty

Baskent University

Status and phase: Unknown; Phase 3

Conditions: Postoperative Pain

Treatments: Drug: Paracetamol; Drug: Dexketoprofen

Study type: Interventional

Funder types: Other

Identifiers

NCT02602197

KA 13/100

Details and patient eligibility

About

The investigators conducted a prospective, randomized, double blind study to compare the effectiveness of intravenous paracetamol and dexketoprofen for preventing pain during first 24 hours postoperative period in adult patient undergoing septoplasty.

Full description

Postoperative pain scores as measured by Visual Analog Scale (VAS) (0 represented no pain and 10 the worst pain ever experienced) at 15, 30, 60 minutes and 2th, 4th, 6th, 12th and 24th hours postoperatively.

Enrollment: 2 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• After patient's inform consent was approved, a total of 70 ASA (American Society of Anesthesiology) physical status I and II adult patients age 18 to 65 undergoing septoplasty were planned include the study.

Exclusion criteria

• History of clotting disorders or blood dyscrasias,
• Gastrointestinal ulcer or chronic dyspepsia,
• History of allergy to the study drugs,
• Active bleeding or bleeding disorders.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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2 participants in 2 patient groups

Paracetamol

Active Comparator group

Description:

1 gr paracetamol received intravenously bolus 15 minutes after anesthetic induction and at the postoperative 6 th,12 th, 18 th and 24 th hours

Treatment:

Drug: Paracetamol

Dexketoprofen

Active Comparator group

Description:

50 mg dexketoprofen received intravenous bolus 15 minutes after anesthetic induction and at the postoperative 8 th,16 th and 24 th hours.

Treatment:

Drug: Dexketoprofen