Intravenous Pertussis Immune Globulin in Patients With Severe Childhood Pertussis Infection

IWK Health Centre

Status and phase: Completed; Phase 3

Conditions: Whooping Cough; Pertussis

Treatments: Drug: immune globulin

Study type: Interventional

Funder types: Other

Identifiers

NCT00004422

IWK-FDR001044

199/13322

P9701

Details and patient eligibility

About

OBJECTIVES:

Assess the efficacy of a single infusion of a high titer pertussis immune globulin for the treatment of severe pertussis in children.

Full description

PROTOCOL OUTLINE: This is a randomized, multicenter study. Patients are randomized to receive an infusion of either pertussis immune globulin or placebo (0.9% saline).

Patients are followed every 2 weeks for up to 6 months.

Completion date provided represents the completion date of the grant per OOPD records

Sex: All

Ages: Under 5 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Documented infection with Bordetella pertussis