Intravenous Tramadol Versus Intravenous Paracetamol in Patients With Dysmenorrhea

Cairo University (CU)

Status and phase

Completed

Phase 4

Conditions

Dysmenorrhea

Treatments

Drug: tramadol

Drug: paracetamol

Study type

Interventional

Funder types

Other

Identifiers

NCT03509740

dysmenorrhea

Details and patient eligibility

About

Patients presented with primary dysmenorrhea composed the study population. One gram paracetamol and 100 mg tramadol in 100 ml saline with a slow infusion were compared in ceasing dysmenorrhea in the emergency department

Full description

Patients over 18 years old who presented with dysmenorrhea composed the study population. Patients received painkiller within the last six hours, physical findings consistent with peritoneal irritation, allergy to the study drugs, renal or liver failure, drug addiction, pregnancy or woman with lactation and denied to give inform consent were the exclusion criteria. The pain of the study patients is measured with the visual analogue scale at baseline, 15th and 30th minutes and 1 hour after study drug administration. At the end of the 60 minutes, rescue drug need is also recorded.

Enrollment

100 patients

Sex

Female

Ages

18 to 35 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with moderate to severe primary dysmenorrhea and visual analog scale (VAS) pain scores ≥40
Patients over 18 years old

Exclusion criteria

denied to give inform consent, irregular menstrual cycles, known or suspected secondary dysmenorrhea
Renal or liver failure
Allergy to the study drugs
Receiving pain killer within the last 6 hours.
Physical examination findings consistent with peritoneal irritation
Pregnancy or patients with lactation
Drug or Alcohol Abuse