Intravenous Versus Intra-peritoneal Dexamethasone on the Incidence of Postoperative Nausea and Vomiting

Assiut University

Status: Completed

Conditions: Postoperative Nausea and Vomiting

Treatments: Drug: Intravenous Dexamethasone; Drug: Intraperitoneal Dexamesathone

Study type: Interventional

Funder types: Other

Identifiers

NCT02947672

01003060377

Details and patient eligibility

About

Effect of intravenous versus intra-peritoneal dexamethasone on the incidence of postoperative nausea and vomiting following Laparoscopic gynecological surgeries.

Enrollment: 100 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adult Female patients
2. American society of anesthesiologist class I & II
3. Undergoing Laparoscopic gynecological surgeries

Exclusion criteria

1. Patient refusal to participate in the study
2. Patients with coagulopathy or under anticoagulation therapy.
3. Infection near the site of needle insertion.
4. Body mass index > 40kg/m2
5. Patients with any neurological or neuromuscular disorder or history of seizures.
6. Known allergy to any drug used in the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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100 participants in 2 patient groups

Intravenous dexamethasone

Active Comparator group

Description:

50 patients will receive intravenous dexamethasone

Treatment:

Drug: Intravenous Dexamethasone

Intra peritoneal dexamethasone

Active Comparator group

Description:

50 patients will receive intraperitoneal dexamethasone

Treatment:

Drug: Intraperitoneal Dexamesathone