Intravitreal Bevacizumab for Age-Related Macular Degeneration

Asociación para Evitar la Ceguera en México

Status and phase: Terminated; Phase 2

Conditions: Age Related Macular Degeneration

Treatments: Drug: bevacizumab intravitreal injection

Study type: Interventional

Funder types: Other

Identifiers

NCT00347165

AvastinDMRE

Details and patient eligibility

About

The purpose of this study is to determine whether intravitreal injection of bevacizumab is effective in the treatment of neovascular age related macular degeneration

Full description

The neovascular age related macular degeneration(AMD) is a important cause of legal blindness in adults older than 50 years. Currently the treatment is photodynamic therapy that offer stabilization and limited visual improvement after 2 years of therapy. Bevacizumab has been reported effective used as intravenous injection for AMD. But serious side effects have been reported with the use of this drug in oncologic patients. The intravitreal use has been reported in limited case reports and safety and efficacy should be determined.

The purpose of this study is efficacy and safety of 2.5 mg intravitreal of bevacizumab for AMD

Enrollment: 50 patients

Sex: All

Ages: 50 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age >50 age related macular degeneration

Exclusion criteria

• moderate to severe cataract glaucoma intraocular surgery diabetes mellitus non controlled hypertension coronary artery disease

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)