Intravitreal Diclofenac Versus Avastin as Primary Treatment of Diffuse Diabetic Macular Edema

Shahid Beheshti University of Medical Sciences

Status and phase: Unknown; Phase 1

Conditions: Diffuse Diabetic Macular Edema

Treatments: Drug: Diclofenac; Drug: Bevacizumab

Study type: Interventional

Funder types: Other

Identifiers

NCT00999791

8818

Details and patient eligibility

About

Diffuse Macular Edema is the main cause of visual disorders in diabetic patients.

Diclofenac is a cheap drug available in most of treatment centers.in animal studies the safe dosage is identified that can be used in diffuse diabetic macular edema for treatment. in this study, we are going to compare the effect of intra vitreal injection of Diclofenac and Bevacizumab in primary treatment of diffuse diabetic macular edema.

Full description

Diffuse Macular Edema is the main cause of visual disorders in diabetic patients.

Diclofenac is a cheap drug available in most of treatment centers.in animal studies the safe dosage is identified that can be used in diffuse diabetic macular edema for treatment. in this study, we are going to compare the effect of intra vitreal injection of Diclofenac and Bevacizumab in primary treatment of diffuse diabetic macular edema.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with clinically significant macular edema and diffuse macular edema

Exclusion criteria

• any history of focal photocoagulation
• any prior intra ocular injection
• history of glaucoma with high pressure
• history of ophthalmic surgery
• high rish PDR
• active PDR

Trial design

0 participants in 2 patient groups

Avastin

Active Comparator group

Treatment:

Drug: Bevacizumab

Diclofenac

Active Comparator group

Treatment:

Drug: Diclofenac