Intravitreal Injections by Nurses and Physicians Compared

St. Olavs Hospital

Status: Completed

Conditions: Eye Diseases

Treatments: Drug: Anti-VEGF agents; Procedure: intravitreal injections given by a nurse; Procedure: Intravitreal injections; Procedure: intravitreal injections given by a physician

Study type: Interventional

Funder types: Other

Identifiers

NCT02359149

2014/1719

Details and patient eligibility

About

Anti-VEGF agents are given for a variety of previously untreatable eye diseases. The last years indications for their use and consequently the number of patients needing treatment, have been increasing. Most patients require multiple injections. This has resulted in many eye departments administering thousands of injections per year, also at St Olavs University Hospital Trondheim. To cope with this increase in workload, it would be helpful if injections would be given not only by the physicians but also by the nurses. This study's objective is to compare efficiency, patient satisfaction and cost per patient of injections given by nurses and physicians.

Enrollment: 328 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• referred to the eye clinic for treatment of age related macular degeneration, diabetes retinopathy or retinal vein occlusion with anti-vascular endothelium growth factor
• Ability to provide written informed consent
• ability to comply with study assessments for the full duration of the study

Exclusion criteria

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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328 participants in 2 patient groups

nurse

Experimental group

Description:

intravitreal injections with anti-VEGF agents given by a nurse

Treatment:

Procedure: intravitreal injections given by a nurse

Procedure: Intravitreal injections

Drug: Anti-VEGF agents

physician

Active Comparator group

Description:

intravitreal injections with anti-VEGF agents given by a physician

Treatment:

Procedure: intravitreal injections given by a physician

Procedure: Intravitreal injections

Drug: Anti-VEGF agents