Intravitreal Triamcinolone for Acute Branch Retinal Vein Occlusion

Shahid Beheshti University of Medical Sciences

Status and phase: Completed; Phase 2

Conditions: Branch Retinal Vein Occlusion

Treatments: Drug: Triamcinolone

Study type: Interventional

Funder types: Other

Identifiers

NCT00370266

8247

Details and patient eligibility

About

The purpose of this study is to determine whether intraocular injection of triamcinolone is effective in the treatment of macular edema in acute branch retinal vein occlusion.

Full description

Intravitreal triamcinolone has recently been shown to have beneficial effect on chronic macular edema due to vein occlusion and preventive effect on neovascularization. Hypothetically, prevention of macular derangement by reducing the amount of edema from early phase after occlusion until restoration of collaterals seems to be helpful in these eyes. To our knowledge, no prospective randomized clinical trial, considering both macular changes and preventive effect on neovascularization has been published for intravitreal triamcinolone in acute branch retinal vein occlusion.

Enrollment: 30 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Eyes suffering from branch retinal vein occlusion with less than 2 months duration.

Exclusion criteria

• Monocularity,
• Previous intraocular surgery or laser therapy
• Glaucoma or ocular hypertension
• Significant media opacity
• Existence of traction on the macula
• Visual acuity ≥20/40
• Signs of chronicity (such as cilioretinal and/or retinal shunt vessels)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind