Inulin-type Fructans-rich Vegetables, Obesity, Gut Microbiota (Food4Gut)

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status

Completed

Conditions

Obesity

Treatments

Dietary Supplement: Placebo

Dietary Supplement: Inulin

Study type

Interventional

Funder types

Other

Identifiers

NCT03852069

B403201422056

Details and patient eligibility

About

The purpose of the study was to evaluate the effect of a diet based on ITF-rich vegetables in combination with purified ITF supplementation on weight management, metabolic alteration and gut microbiota composition. Obese patients were treated for 3 months and several parameters were measured before and after the study period.

Enrollment

106 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Body mass index > 30 kg/m²
Caucasian
Presence of at least one of the following comorbidity : prediabetes, diabetes, dyslipidemia, hypertension, steatosis.

Exclusion criteria

Psychiatric problems or use of antipsychotic
Consumption of antibiotics, pro/prebiotics, fibre dietary supplement, or any molecules that modifies the intestinal transit (<6 weeks)
Pregnancy in progress or planified within 6 months
Specific dietary practise (vegetarian, vegan,...)
Specific dietary treatment (<6 weeks) (e.g. high protein diet)
Type 1 diabetes
Excessive alcohol consumption (>3 glasses/day)
Inconclusive acceptability test (regarding the protocol of the intervention and the vegetables used in the protocol)