Invasive Group A Streptococcal Infection (ISAI)

Association Clinique Thérapeutique Infantile du val de Marne

Status: Enrolling

Conditions: Sepsis Due to Streptococcus, Group A; Therapy; Risk Factors; Severe Infection; Medical Complications; Outcome, Fatal; Virulence Factors; Strain; Medical Care

Study type: Observational

Funder types: Other

Identifiers

NCT05788861

ISAI

Details and patient eligibility

About

This study is observational, retrospective and prospective study in pediatric patients hospitalized with invasive streptococcal A infection

Full description

The main of this study is to identify and record cases of invasive and severe infections due to Streptococcus pyogenes. In order to evaluate the incidence of severe forms of disease and the possible contributing factors, and to optimize their management.

Admitted patients to intensive care or critical care units in reported via Santé Publique France may also be included in this study.

Secondly, epidemiological, clinical, bacteriological data of all severe or not cases, of group A Streptococcal infections will be compiled to describe their characteristics, and try to explain this recrudescence as well as possible.

Enrollment: 100 estimated patients

Sex: All

Ages: 1 day to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age<18 years
• Documented invasive Group A Streptococcus infection (identification of GAS in a normally sterile site or from another site in case of toxin shock or necrotizing dermo-hypodermatitis)

Exclusion criteria

• Opposition of the patient or his/her legal representative