Invasive PGT-A Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection

Assisting Nature

Status: Enrolling

Conditions: Chromosome Abnormality; Aneuploidy; Infertility

Treatments: Diagnostic Test: embryo selection

Study type: Observational

Funder types: Other

Identifiers

NCT05547555

AN010

Details and patient eligibility

About

This is a prospective randomised study of the evaluation of the clinical IVF results after invasive PGT-A embryo selection versus Non-invasive PGT-A assisted embryo selection in subfertile women.

Full description

A randomized prospective study focusing on subfertile women undergoing IVF treatment followed by embryo transfer on the blastocyst stage.

Women assigned to group A proceed to embryo transfer, after invasive PGT-A embryo selection, while women of group B after non-invasive PGT-A assisted embryo selection.

IVF outcomes, regarding the success rate of the trasnfer and the time required to achieve conception is studied in both groups.

Enrollment: 200 estimated patients

Sex: Female

Ages: 40 to 54 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women who followed IVF treatment
• 40 years old or older
• Single embryo transfer
• blastocyst stage cultured embryos

Exclusion criteria

• women under the age of 40 years
• not blastocyst transfer (transfers performed at earlier embryo stage)
• double embryotransfer
• women who had embryotransfer according to morphological criteria women whose embryos were not time-lapse monitored

Trial design

200 participants in 2 patient groups

INVASIVE PGT-A

Description:

Women who proceed to embryo transfer after invasive PGT-A embryo selection.

Treatment:

Diagnostic Test: embryo selection

NON INVASIVE PGT-A

Description:

Women who proceed to embryo transfer after non- invasive PGT-A embryo selection.

Treatment:

Diagnostic Test: embryo selection