Invasive Pneumococcal Disease Study

Association Clinique Thérapeutique Infantile du val de Marne

Status: Enrolling

Conditions: Mortality; Pneumococcal Conjugate Vaccine; Pneumococcal Infections; Antibiotic Treatment

Treatments: Other: observational study

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT04664556

IPD

Details and patient eligibility

About

After 7 then 13 valent pneumococcal conjugate vaccine implementation in France in children, we will evaluate the impact of this vaccination on invasive pneumococcal disease (IPD). We will describe the clinical characteristics of IPD, pneumococcus serotyping, underlying conditions and vaccination status.

Enrollment: 1,369 estimated patients

Sex: All

Ages: 1 day to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Isolate of Streptococcus pneumoniae from at least one blood culture, or pleural fluid, or joint fluid, or cerebrospinal fluid or other normally sterile body site, or if there is a positive blood PCR.

Exclusion criteria

• Pneumococcal strain not transmetted to National Reference Center for Pneumococci or to Regional Pneumococci Observatory

Trial design

1,369 participants in 1 patient group

Cohort of invasive pneumococcal disease in children

Treatment:

Other: observational study