Investigating Myocardial Remodelling in the Failing Human Heart (RELAX)

University of Oslo (UIO)

Status: Enrolling

Conditions: Heart Failure

Study type: Observational

Funder types: Other

Identifiers

NCT05303896

230524

Details and patient eligibility

About

Despite improvements in therapy, heart failure is a disease with high mortality and accelerating prevalence. To improve patient care, it is necessary to better understand the features and underlying mechanisms of myocardial remodeling; how it manifests in vivo and its underlying cellular and extracellular changes. The RELAX study will offer insight into myocardial remodeling, by comprehensively assessing function and structure of failing human hearts, and investigate its underlying cellular and extracellular changes.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Eligible for heart transplantation
• Willingness to participate in the present study and ability to understand and sign the written informed consent

Exclusion criteria

• Patients under the age of 18.