Investigating Physiological Adaptations to Weight Loss

University of Melbourne

Status: Completed

Conditions: Obesity

Treatments: Dietary Supplement: Optifast VLCD

Study type: Interventional

Funder types: Other

Identifiers

NCT00870259

HP 508920

Details and patient eligibility

About

The purpose of this study is to examine the effect of diet-induced weight loss on the levels of circulating nutrients and hormones which are involved in feelings of hunger and satiety.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• males and post-menopausal females
• aged over 18 years
• BMI 27-40kg/m2
• weight-stable

Exclusion criteria

• major comorbid medial condition (including diabetes)
• taking medications known to affect weight
• smoking

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)