Investigating the Effects of Krill Oil and Krill Protein on Post-exercise Muscle Protein Metabolism (KIPLING)

University of Glasgow

Status: Enrolling

Conditions: Hypertrophy

Treatments: Dietary Supplement: Carbohydrate; Dietary Supplement: Krill protein; Dietary Supplement: Vegetable oil; Dietary Supplement: Krill oil

Study type: Interventional

Funder types: Other

Identifiers

NCT05774444

KIPLING

Details and patient eligibility

About

The aim of the current study is to find out if krill oil can increase muscle building processes in response to resistance (weightlifting) type exercise. Others aim are to determine the effects of krill protein, and the interaction of krill oil and protein, on muscle building processes in response to resistance (weightlifting) type exercise.

Enrollment: 48 estimated patients

Sex: All

Ages: 60 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Be 60 years old or older
• Have a BMI of less than 35kg/m2
• Be participating in structured exercise for less than 2h per week

Exclusion criteria

• Diabetes
• Severe cardiovascular disease
• Seizure disorders,
• Uncontrolled hypertension (>150/90mmHg at baseline measurement)
• Cancer or cancer that has been in remission <5 years
• Ambulatory impairments which would limit ability to perform assessments of muscle function
• Dementia
• Taking medication known to affect muscle (e.g., steroids)
• Have an implanted electronic device (e.g., pacemaker/defibrillator/insulin pump),
• Anticoagulant therapy
• Allergies to seafood
• Regular consumption of more than 1 portion of oily fish per week.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

48 participants in 4 patient groups, including a placebo group

Vegetable oil + Carbohydrate

Placebo Comparator group

Description:

The vegetable oil will be a placebo control for the Krill oil (4g/day). The carbohydrate will be a placebo control for the Krill protein (20g)

Treatment:

Dietary Supplement: Vegetable oil

Dietary Supplement: Carbohydrate

Vegetable oil + Krill protein

Experimental group

Description:

The vegetable oil will be a placebo control for the Krill oil (4g/day). Krill protein will be our active intervention (20g)

Treatment:

Dietary Supplement: Vegetable oil

Dietary Supplement: Krill protein

Krill oil + Carbohydrate

Experimental group

Description:

The Krill oil will be the active supplement for the intervention (4g/day). The carbohydrate will be a placebo control for the Krill protein (20g)

Treatment:

Dietary Supplement: Krill oil

Dietary Supplement: Carbohydrate

Krill oil + Krill protein

Experimental group

Description:

Both the Krill oil (4g/day) and the Krill protein will be the active intervention supplements (20g)

Treatment:

Dietary Supplement: Krill oil

Dietary Supplement: Krill protein