Investigating the Role of EN in NTIS Among Fistula Patients (EN;NTIS)

Jinling Hospital, China

Status: Completed

Conditions: Gastrointestinal Fistula

Study type: Observational

Funder types: Other

Identifiers

NCT02038504

81270478 (Other Identifier)

NTIS-EN-1

Details and patient eligibility

About

The purpose of this study is to investigate whether enteral nutrition are effective in the treatment of nonthyroidal illness syndrome among fistula patients.

Full description

Nonthyroidal illness syndrome (NTIS) is a common alterations in thyroid function observed in about 70% of hospitalized patients, with or without acute systemic illnesses. Mechanisms in the pathogenesis of NTIS are not yet well understood. Our previous study demonstrated that NTIS occurred frequently with a prevalence of 57.5% in gastrointestinal fistulas patients. In recent study, it has been shown that early enteral nutrition decreases the duration of hospitalization and mortality in the burn population, indicating a potential role of enteral nutrition in NTIS.In addition, the management of fistula patients requires bundle therapy including Nutrition therapy, especially enteral nutrition.The purpose of this study is to investigate whether enteral nutrition are effective in the treatment of nonthyroidal illness syndrome among fistula patients.

Enrollment: 40 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of gastrointestinal fistula
• Clinical diagnosis of nonthyroidal illness syndrome
• Using enteral nutrition for fistula management

Exclusion criteria

• patients who were prescribed drug which may affect thyroid function before or in our study
• patients who were diagnosed as primary thyroid disease

Trial design

40 participants in 1 patient group

gastrointestinal fistula