Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using Multi-exponential T2 Components

AHS Cancer Control Alberta

Status: Unknown

Conditions: Glioma

Study type: Observational

Funder types: Other

Identifiers

NCT00813787

CNS-24534

Details and patient eligibility

About

The purpose of this study is to see if a specialized imaging technique using MRI called multi-exponential T2 component analysis can reliably differentiate between normal brain and brain tumour.

Full description

Existing methods of contouring tumours for radiation therapy involve manual interpretations of qualitative diagnostic images. These methods, being qualitative, do not offer a consistent and reproducible platform for contouring, making it difficult to evaluate the effects of contouring choices on treatment outcome. T2 component analysis in MRI has the potential to offer a quantitive basis for identifying tumor tissue- this potential is investigated in this pilot study.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Eighteen years of age or older
• Clinical subjects must have not yet begun radiation therapy
• Must have signed our study-specific consent form

Exclusion criteria

Trial design

20 participants in 2 patient groups

A. glioma

Description:

A. glioma population

B. Normal brain

Description:

B. Normal brain