Investigation of Changes in Lower Limb Muscles After Cerebrovascular Accident

Universitaire Ziekenhuizen KU Leuven

Status: Completed

Conditions: Cerebrovascular Accident

Treatments: Diagnostic Test: 3DfUS and IPSA of leg muscles

Study type: Observational

Funder types: Other

Identifiers

NCT04607486

S60153

Details and patient eligibility

About

The aim of this study is to investigate lower limb muscles after cerebrovascular accident

Full description

The aim of this study is to define and differentiate the changes in MMT properties related to the alterations in muscle tone of the lower limb in first-ever chronic stroke patients by using a 3D free-hand Ultrasonography (3DfUS) technique in combination with an instrumented spasticity assessment (IPSA). In these chronic stroke patients, the spontaneous neurological recovery is stabilized

Enrollment: 76 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Definition of case population :

  o first ever stroke with spasticity of the lower limb.

• Definition of control :

  • first ever stroke without spasticity of the lower limb
  • healthy aged-matched subjects

Exclusion criteria

• Musculoskeletal or neurological problems affecting the lower limb
• Presence of other neurological pathology that could lead to spasticity, ataxia, dystonia
• Cognitive problems that impede measurements
• Severe co-morbidities
• Peripheral spastic medication

Trial design

76 participants in 3 patient groups

CVA and spasticity

Description:

Adults with first-ever chronic CVA and leg spasticity

Treatment:

Diagnostic Test: 3DfUS and IPSA of leg muscles

CVA without spasticity

Description:

Control group

Treatment:

Diagnostic Test: 3DfUS and IPSA of leg muscles

healthy subjects

Description:

Control group

Treatment:

Diagnostic Test: 3DfUS and IPSA of leg muscles