Investigation of Desmoplastic Squamous Cell Carcinoma (DesmoPEK)

University Hospital Tuebingen

Status: Unknown

Conditions: Squamous Cell Carcinoma of the Skin

Treatments: Procedure: Immunohistochemistry using Pancytokeratin Staining

Study type: Interventional

Funder types: Other

Identifiers

NCT02717936

DESMOPEK1

Details and patient eligibility

About

Aim of the study is to verify wether it is possible to have a more sensitive diagnostic tool using pancytokeratin immunohistochemistry for desmoplastic squamous cell carcinoma compared to regular H&E staining. The investigators therefore plan to include 73 participants with a confirmed diagnosis of desmoplastic squamous cell carcinoma and do regular follow up.

Enrollment: 73 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• desmoplastic squamous cell carcinoma (SCC) of the skin

Exclusion criteria

• tumor recurrence
• collision tumors
• other skin malignancies
• progeria
• Rothmund-Thomson-Syndrome
• lacking of the capacity for informed consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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73 participants in 1 patient group

Immunohistochemistry

Other group

Description:

Patients are investigated using immunohistochemistry with Pancytokeratin

Treatment:

Procedure: Immunohistochemistry using Pancytokeratin Staining