Investigation of Dysregulated Signaling in MPD Via Multiparameter Phospho-specific Flow Cytometry

Stanford University

Status: Terminated

Conditions: Myeloproliferative Disorders; Myeloproliferative Disorders (MPD)

Study type: Observational

Funder types: Other

Identifiers

NCT01144780

HEMMPD0011 (Other Identifier)

IRB-14723

SU-07092009-3060 (Other Identifier)

Details and patient eligibility

About

The objective of this study is to better understand the underlying pathogenetic mechanisms of myeloproliferative disorders (MPDs). We will collect peripheral blood samples from MPD patients and utilize multiparameter phospho-specific flow cytometry to investigate dysregulated signaling in blood cells from these patients. This will provide deeper insights into the pathogenesis of MPDs and may lead to the identification of novel targets for therapeutic intervention.

Enrollment: 10 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Any patient who carries a diagnosis of a myeloproliferative disorder (MPD). Exclusion Criteria:Any patient who is not willing to give consent.