Investigation of Genetic Disease Marker Associated With Spontaneous Haemorrhagic Stroke Complicating Severe Pre-eclampsia in Pregnancy

Asfendiyarov Kazakh National Medical University

Status: Completed

Conditions: Hemorrhagic Stroke; Eclampsia

Treatments: Genetic: SNP analysis of the DNA

Study type: Observational

Funder types: Other

Identifiers

NCT05121415

1189

Details and patient eligibility

About

To search for a genetic marker of hemorrhagic stroke complicating severe eclampsia, a single nucleotide polymorphism (SNP) analysis of DNA obtained from the peripheral blood of patients with hemorrhagic stroke and normal control will be performed.

Full description

Detailed Description:

Unrelated Korean subjects who have Spontaneous hemorrhagic stroke complicating severe eclampsia in pregnancy were recruited in the current study. Genotyping for various SNP associated due to the linkage disequilibrium patterns is to be performed. Genotypes would be statistically compared between patients with hemorrhagic stroke and normal control subjects free of hemorrhagic stroke

Enrollment: 100 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

-patients with hemorrhagic stroke complicating severe eclampsia in pregnancy

Exclusion criteria

patients without hemorrhagic stroke complicating severe eclampsia in pregnancy

Trial design

100 participants in 2 patient groups

Experimental group:

Description:

patients with hemorrhagic stroke complicating severe pre-eclampsia in pregnancy

Treatment:

Genetic: SNP analysis of the DNA

Control group

Description:

patients without hemorrhagic stroke complicating severe pre-eclampsia in pregnancy

Treatment:

Genetic: SNP analysis of the DNA