Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for r/m NPC

Sun Yat-sen University

Status: Not yet enrolling

Conditions: Recurrent and Metastatic Nasopharyngeal Carcinoma; Multi-omics Technique; Nasopharyngeal Carcinoma; Efficacy of Chemoradiotherapy and Immunotherapy

Treatments: Drug: cisplatin-based chemoradiotherapy combined with immunotherapy

Study type: Observational

Funder types: Other

Identifiers

NCT06197776

multi-omics technique in NPC

Details and patient eligibility

About

The observational clinical study will recruit 50 recurrent and/or metastatic nasopharyngeal carcinoma (r/mNPC) patients, to investigate the prediction values of multi-omics technique for the efficacy of chemoradiotherapy combined with immunotherapy.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Recurrent or metastatic nasopharyngeal carcinoma patients
• All genders，range from 18～70 years old
• ECOG score 0 ~ 1
• Inform consent form

Exclusion criteria

• Have or are suffering from other malignant tumors;
• Participating in other clinical trials;
• Drug or alcohol addition;
• Do not have full capacity for civil acts;
• Mental disorder;
• Pregnancy or lactation;
• Severe complication, eg, uncontrolled hypertension.

Trial design

50 participants in 1 patient group

chemoradiotherapy combined with immunotherapy

Description:

Patients treated with chemoradiotherapy combined with immunotherapy

Treatment:

Drug: cisplatin-based chemoradiotherapy combined with immunotherapy