Investigation of Neurophysiological Functioning During Oral Comprehension Task (COraIL)

Grenoble Alpes University Hospital Center (CHU)

Status: Enrolling

Conditions: Learning; Comprehension; Language

Treatments: Diagnostic Test: imaging; Diagnostic Test: behavior; Diagnostic Test: physiology

Study type: Observational

Funder types: Other

Identifiers

NCT06178276

2023-A01939-36 (Other Identifier)

38RC23.0309

Details and patient eligibility

About

The oral comprehension (OC) of a second language (L2) involves different cognitive processes, specially during the learning phase. This study aims at investigating the neurophysiological functioning of different steps involved in this oral understanding.

Full description

Here, the investigators seek for the different neurophysiological processes involved in OC according to the level of understanding (2 levels) and its different phases (fluid, hindered and metacognitive feedback).

This study therefore requires three different research methodologies :

1. an interactive system dedicated to the boundary delimitations of obstacles during OC
2. an investigation of the autonomic nervous system responses (measurement of electrodermal activity and heart rate variability) that will likely occur differently during different phases of the OC process
3. an investigation of the central responses (through fMRI technique), coupled with autonomous responses, that will identify the different neural networks in the different stages of the OC process.

Enrollment: 70 estimated patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• French learner in Italian language
• right-handed
• affiliated to French social security
• informed consent signed

Exclusion criteria

• pregnant woman
• audiologic pathology impacting the capacity of hearing
• neurologic or psychiatric pathology that may interfere with oral comprehension
• learning disability (for instance: dyslexia)
• contra-indication to MRI and to EDA acquisition

Trial design

70 participants in 2 patient groups

A2 level

Description:

Level of oral comprehension in italian language

Treatment:

Diagnostic Test: behavior

Diagnostic Test: physiology

Diagnostic Test: imaging

B2 level

Description:

Level of oral comprehension in italian language

Treatment:

Diagnostic Test: behavior

Diagnostic Test: physiology

Diagnostic Test: imaging