Investigation of the Effectiveness of CoronaVac Vaccine in Cancer Patients With Active Chemotherapy and Comparison With Healthy People.

Asoc. Prof. Erdoğan Selçuk Şeber

Status: Unknown

Conditions: Is the Coronovac Vaccine Effective in Patients Receiving Chemotherapy

Treatments: Biological: CoronoVAC

Study type: Observational

Funder types: Other

Identifiers

NCT04765215

CHEMOCOVAC

Details and patient eligibility

About

This study aimed to investigate the effectiveness of CoronaVac vaccine, which is more than 90% protective in healthy people, in cancer patients receiving active chemotherapy. In this study, to collect information to measure the amount of antibodies produced by the vaccine in the blood of volunteers with the CoronoVac vaccine and to compare it with healthy volunteers.

Enrollment: 291 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Group 1

  1. 18 years old and above
  2. Having completed two doses of CoronoVac vaccine on time
  3. Those with a pathological diagnosis of breast cancer or lung cancer
  4. Being the first dose of vaccine during active chemotherapy period
  5. Ecog performance score 0-1
  6. Patients who signed the informed voluntary consent form

• Group 2

  1. Over 18 years old
  2. Ecog performance score is 0-1
  3. Those who have completed 2 doses of coronovac vaccine within the recommended period
  4. Volunteer who signed the informed consent form

Exclusion criteria

• For all groups

  1. Being confirmed or suspected covid-19 before vaccination
  2. Symptomatic covid-19 infection
  3. Being addicted to alcohol or drugs
  4. Having a fever of 37.8 ° C as a suspect before vaccination
  5. Aspleni

Trial design

291 participants in 2 patient groups

Breast or lung cancer patients receiving active chemotherapy and 2 doses of CoronaVac vaccine

Treatment:

Biological: CoronoVAC

Healthy volunteers who received two doses of coronavac vaccine

Treatment:

Biological: CoronoVAC