Investigation of Vascular Pathology in Eye Diseases Using Using Optical Coherence Tomography Angiography (OCT-A)

Insel Gruppe AG, University Hospital Bern

Status: Completed

Conditions: Retinal Disease

Treatments: Device: optical coherence tomography angiography

Study type: Observational

Funder types: Other

Identifiers

NCT02811536

OCTA Bern

Details and patient eligibility

About

Comparison of OCTA to conventional imaging modalities for the diagnosis of eye diseases

Full description

Optical coherence tomography angiography (OCTA) is a new non-invasive imaging technique that employs motion contrast imaging to high-resolution volumetric blood flow information. OCTA compares the decorrelation signal between sequential OCT b-scans taken at precisely the same cross-section in order to construct a map of blood flow. At present, level 1 evidence of the technology's clinical applications doesn't exist. The investigators plan to compare OCTA as an imaging modality to conventional imaging modalities used in clinical routine.

Enrollment: 440 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patients from the Department of Ophthalmology, University Hospital Bern requiring conventional imaging for eye disease and willing to sign informed consent Patients of 18 years or older

Exclusion criteria

Patients not willing or able to sign informed consent Patients younger than 18 years Patients with epilepsy Patients having had photodynamic therapy within the last 48 hours prior to imaging with OCTA

Trial design

440 participants in 8 patient groups

Diabetic retinopathy

Description:

Patients with various degrees of diabetic retinopathy

Treatment:

Device: optical coherence tomography angiography

Retinal detachment

Description:

Patients with a history of retinal detachment

Treatment:

Device: optical coherence tomography angiography

Retinal vein occlusion

Description:

Patients with a history of retinal vein occlusion

Treatment:

Device: optical coherence tomography angiography

Arterial hypertension

Description:

Patients with a history of arterial hypertension

Treatment:

Device: optical coherence tomography angiography

Carotid artery occlusion

Description:

Patients with a history of carotid artery occlusion

Treatment:

Device: optical coherence tomography angiography

Age related macular degeneration

Description:

Patients with a history of Age related macular degeneration

Treatment:

Device: optical coherence tomography angiography

Macroaneurysms

Description:

Patients with a history of retinal macroaneurysms

Treatment:

Device: optical coherence tomography angiography

Central serous chorioretinopathy

Description:

Patients with a history of central serous chorioretinopathy

Treatment:

Device: optical coherence tomography angiography