INvestigational Study Into Transplantation of the Uterus (INSITU)

Womb Transplant UK

Status: Unknown

Conditions: Asherson's Syndrome; Mayer-Rokitansky-Kuster Syndrome; Cervical Cancer; Postpartum Hemorrhage

Study type: Observational

Funder types: Other

Identifiers

NCT04244409

WombTransplantUK

Details and patient eligibility

About

Observational study on cohort of 10 women undergoing uterine transplantation using deceased donors

Enrollment: 10 estimated patients

Sex: Female

Ages: 24 to 38 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Female

2. Age - 24-38 (or 40 if eggs frozen <38)

3. AUFI

   1. Normal length vagina
   2. No renal pathology

4. BMI <30kg/m2

5. ASA grade I

6. Meet psychological criteria

7. Meet HFEA criteria for IVF

8. Eligible for NHS treatment

9. Speak fluent English

Exclusion criteria

1. Unsuccessful oocyte retrieval (<10 good quality embryos)
2. Previous multiple/significant surgeries
3. Severe endometriosis
4. Cancer patients <5 years in remission
5. Previous living childbirth, adopted child or child born through surrogacy
6. HIV or Hepatitis B / C positive
7. Skin or intestinal neovagina